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Molecular Characterization TXCCR Laboratories

Molecular Characterization

David Wheeler, PhD

Baylor College of Medicine

When funding is available, selected cell lines and PDXswill have genome-wide expression profiling data obtained and assessment of genomic changes (mutations, deletions, fusions, and SNPS) determined in Dr. Wheeler's laboratory. As molecular data on the models are assembled, cluster analysis will seek relationships between between cell lines, xenografts, and data taken from human tumor samples.